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Identification

CAS Number

40732-48-7

Name

Guanosine3',5'-cyclicmonophosphatesodiumsalt

Synonyms

(4aR,6R,7R,7aS) 2-Oxyde de 6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytétrahydro-4H-furodioxaphosphinin-2-olate et de sodium 255-056-0 3',5'-cGMP-Na3',5'-Cyclic GMP monosodium salt40732-48-7 6H-Purin-6-one, 2-amino-3,9-dihydro-9--1,3,2-dioxaphosphorin-6-yl]-, sodium salt (1:1) cGMPCyclic GMPCyclic GMP sodium saltGuanosine 3',5'-cyclophosphate monosodium saltMFCD00038424 Natrium-(4aR,6R,7R,7aS)-6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furodioxaphosphinin-2-olat-2-oxid Sodium (4aR,6R,7R,7aS)-6-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furodioxaphosphinin-2-olate 2-oxide sodium 3',5'-cyclic gmp anionSODIUM GUANOSINE CYCLIC MONOPHOSPHATE,5ʹ 3',5'-cyclic Guanosine monophosphate3′,5′-cGMP-Na3′,5′-Cyclic GMP monosodium saltcyclic 3',?5'-?(hydrogen phosphate) guanosine, monosodium saltCyclic GMP sodiumCyclic GMP, G-3,5-MP, cGMP, Na-cyclic Monophosphate, Sodium Salt - CAS 40732-48-7 - CalbiochemGuanosine 3ʹGuanosine 3ʹ,5ʹ-cyclic Monophosphate, Sodium Salt - CAS 40732-48-7 - CalbiochemGuanosine 3',5'-Cyclic Monophosphate Sodium SaltGuanosine 3’5’-cyclic Monophosphate, Sodium SaltGuanosine 3′,5′-cyclic monophosphate sodium saltGuanosine 3′,5′-cyclophosphate monosodium saltGuanosine 3'5'-cyclic Monophosphate, Sodium SaltGuanosine-3':5'-cyclic monophosphate monosodium saltGuanosine3:5-cyclicmonophosphatesodiumsaltGUANOSINE3':5'-CYCLICMONOPHOSPHATESODIUMSALTsodium (4aR,6R,7R,7aS)-6-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2??-furodioxaphosphinin-2-olate

SMILES

c1nc2c(n13(4(O3)COP(=O)(O4))O)c(nc2=O)N.

StdInChI

InChI=1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

StdInChIKey

KMPIYXNEROUNOG-GWTDSMLYSA-M

Molecular Formula

C10H11N5NaO7P

Molecular Weight

367.187

MDL Number

MFCD00038424

Properties

Appearance

White powder

Safety Data

Symbol

Signal Word

Warning

WGK Germany

3

MSDS Download

Specifications and Other Information of Our Guanosine3',5'-cyclicmonophosphatesodiumsalt CAS 40732-48-7

Purity

99% min

Loss on Drying

≤7.0%

EmM UV-vis spectrum, dry basis PH 7.0

14.08

Shelf Life

1 year

Storage

-20℃, sealed well and away from light

Known Application

Sodium Guanosine-3',5'-Cyclic Monophosphate (cGMP-Na) has several important applications in biochemistry, pharmacology, and biotechnology.

1. Signal Transduction Research

- cGMP acts as an intracellular second messenger, playing a critical role in various biological signal transduction processes, such as smooth muscle relaxation, vasodilation, and neural signaling.

- It is widely used to study guanylate cyclase activity and cGMP-dependent signaling pathways.

2. Pharmacological Studies

- Used to investigate the effects of drugs targeting cGMP-related pathways, such as treatments for hypertension, erectile dysfunction (e.g., mechanisms of phosphodiesterase-5 inhibitors), and cardiovascular diseases.

- Aids in new drug development and the evaluation of drug effects on cGMP-related processes.

3. Enzymology Research

- Serves as a substrate for cGMP-dependent protein kinases and phosphodiesterases, enabling studies of enzyme mechanisms and their regulatory functions.

4. Cellular and Molecular Biology

- Facilitates research on cGMP's role in cell proliferation, differentiation, and apoptosis.

- Applied in cellular models or tissue culture experiments to explore signaling pathway regulation.

General View of Documents

Links

This product is developed by our R&D company Ulcho Biochemical Limited (http://www.ulcho.com/).

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