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Identification

CAS Number

25812-30-0

Name

Gemfibrozil

Synonyms

2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid247-280-2 25812-30-0 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentansäure Acide 5-(2,5-diméthylphénoxy)-2,2-diméthylpentanoïque Gemfibrozil Gemfibrozilo gemfibrozilum gevilonMFCD00079335 Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl- Gen-FibroGenlip114772-53-1 1184986-45-5 1881200 2,2-dimethyl-5-(2,5-dimethyl-phenoxy)-pentanoic acid2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure2,2-Dimethyl-5-(2,5-zlyloxy)valeric acid4TX5-(2,5-Dimethylphenoxy)-2,2-DimethylpentamoicAcid5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoic acid5-(2,5-Dimethyl-Phenoxy)-2,2-Dimethyl-Pentanoic Acid5-(2,5-dimethylphenoxy)-2,2-dimethyl-valeric acid5--2,2-dimethylpentanoic acidAusgemBolutolBrozilC07020CholespidCI-7ClearolDB01241DecreliDecrelipElmoganEmfibFetinorFibratolFibrocitGEMGemcorGemfi 1A PharmaGemfibrilGemfibromaxGemfibrosilGEMFIBROZIL-D6GemfibroziloGemfibrozilo gemfibrozilumGemfibrozilum GemhexalGemlipidGemnpidGem-SGen-Fibro®Gevilon UnoGFZGozidHidilHipolixanInnogen IpolipidJezilJezil®KS-5192LanateromLifibronLipazilLipigemLipiraLipizylLipox GemfiLipozidLIPURLitarekLopid Lopid RLopid;CI-719Low-LiLow-LipMicolipNormolipOrganolipidpEINECS 247-280-2PilderpMicolipNormoliPolyxitpPentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pRenabrazinProgemzalpSynbrozilReducelReguliRegulipRenabrazinSineliSinelipSynbrozilTaborcilTentrocTEVA-ATrialminValeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-гемфиброзил جامفيبروزيل 吉非罗齐

SMILES

Cc1ccc(c(c1)OCCCC(C)(C)C(=O)O)C

StdInChI

InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)

StdInChIKey

HEMJJKBWTPKOJG-UHFFFAOYSA-N

Molecular Formula

C15H22O3

Molecular Weight

250.333

EINECS

247-280-2

MDL Number

MFCD00079335

Properties

Appearance

White crystalline powder

Safety Data

Symbol

GHS07

Signal Word

Warning

Hazard statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Identification Methods

HNMR, HPLC

Assay

98% min

Heavy Metals

≤20ppm

Water

≤0.25%

Any other impurity

≤0.08%

Total impurity

≤0.5%

Ethyl formate

≤5000ppm

Shelf Life

3 years

Storage

Under room temperature away from light

Known Application

Gemfibrozil (1), with the chemical name 2,2-dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid, is a fibrate class lipid-regulating medication derived from clofibrate. It was introduced to the market in the United States in 1982. Gemfibrozil overcomes the serious hepatic toxicity associated with earlier lipid-lowering drugs such as clofibrate while retaining its efficacy. It promotes the breakdown of peripheral fat, reduces the hepatic uptake of free fatty acids, thereby decreasing intrahepatic triglyceride formation. Additionally, it inhibits the synthesis of very-low-density lipoprotein (VLDL) and reduces the generation of VLDL.

General View of Documents

Links

This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).

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