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BTB-1 CAS 86030-08-2
- Identification

- Properties

- Safety Data

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Identification

CAS Number

86030-08-2

Name

BTB-1

Synonyms

4-Chlor-2-nitro-1-(phenylsulfonyl)benzol 4-Chloro-2-nitro-1-(phenylsulfonyl)benzene 4-Chloro-2-nitro-1-(phénylsulfonyl)benzène 4-Chloro-2-nitrophenyl phenyl sulfone86030-08-2 Benzene, 4-chloro-2-nitro-1-(phenylsulfonyl)- BTB-1 1-(2,4-dichlorophenyl)-1-cyclopropanecarboxylic acid1-(benzenesulfonyl)-4-chloro-2-nitrobenzene1-Benzenesulfonyl-4-chloro-2-nitrobenzene1-Benzenesulfonyl-4-chloro-2-nitro-benzene2-Benzenesulfonyl-5-chloronitrobenzene4-chloro-2-nitro-1-(phenylsulfonyl)-benzene4-Chloro-2-nitro-1-(phenylsulphonyl)benzene4-Chloro-2-nitrodiphenyl sulfone4-Chloro-2-nitrodiphenyl sulfone; 1-(Benzenesulfonyl)-4-chloro-2-nitrobenzene4-Chloro-2-nitrodiphenyl sulphone4-Chloro-2-nitrodiphenylsulfone87395-64-0 BTB 1BTB1MFCD00052250 N-(1-Hydroxy-2-(hydroxymethyl)-4-(4-octylphenyl)butan-2-yl)acetamideNSC 156750; NSC 658180SS-5790

SMILES

c1ccc(cc1)S(=O)(=O)c2ccc(cc2(=O))Cl

StdInChI

InChI=1S/C12H8ClNO4S/c13-9-6-7-12(11(8-9)14(15)16)19(17,18)10-4-2-1-3-5-10/h1-8H

StdInChIKey

VZDUQPHKUBZMLW-UHFFFAOYSA-N

Molecular Formula

C12H8ClNO4S

Molecular Weight

297.714

Properties

Appearance

White to off-white

Structure

Structure of BTB-1 CAS 86030-08-2

Safety Data

Symbol

Signal Word

Warning

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Identification Methods

HNMR, HPLC

Water

Loss on Drying

Residue on Ignition

Single Impurity

Total Impurities

Shelf Life

2 years

Storage

store at room temperature away from light; Sealed in dry.

Known Application

BTB-1 CAS 86030-08-2 also called 4-CHLORO-2-NITRO-1-(PHENYLSULFONYL)BENZENE, is a selective and ATP-competitive mitotic kinesin Kif18A inhibitor (IC50 = 1.7 ÎĽM); reversibly inhibits microtubule-stimulated Kif18A ATPase activity. BTB-1 shows cell toxicity with an EC50 values of 35.8ÎĽM. HeLa cells treated with 50ÎĽM BTB1 reveals severe defects inspindle morphology and chromosome alignment.Treatment with high concentrations of BTB-1 does not result in elongated spindles.

General View of Documents

Links

This product is developed by our R&D company Watson Bio Limited (https://www.watson-bio.com/).

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