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Identification
CAS Number
461432-26-8
Name
Dapagliflozin
Synonyms
(1S)-1,5-Anhydro-1--D-glucitol (1S)-1,5-Anhydro-1--D-glucitol (1S)-1,5-Anhydro-1--D-glucitol (2S,3R,4R,5S,6R)-2--6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-{4-chloro-3-phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol1ULL0QJ8UC461432-26-8 Dapagliflozin dapagliflozina dapagliflozine dapagliflozinum D-Glucitol, 1,5-anhydro-1-C-phenyl]-, (1S)- Farxiga Forxiga (1S)-1,5-Anhydro-1-C-phenyl]-D-glucitol(1S)-1,5-anhydro-1-c-4-chloro-3-(4-ethoxyphenyl)methylphenyl-d-glucitol(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyl-tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2--6-methylol-tetrahydropyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol(2S,3R,4R,5S,6R)-2-phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hyd roxymethyl)-tetrahydro-2H-pyran-3,4,5-triol(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hydroxymethyl)tetrahy(2S,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol 1204219-80-6 BMS 512148BMS 512148; BMS-512148BMS512148BMS-512148;BMS512148;BMS 512148BMS-512148|Farxiga®|Forxiga®dapagliflozin ????????????dapagliflozin d5dapagliflozin è¾¾æ ¼åˆ—å‡€ Dapagliflozin;BMS 512148Dapagliflozin|BMS 512148dapagliflozin-d5Farxiga®Forxiga®https://www.ebi.ac.uk/chembl/compoundreportcard/CHEMBL429910/MFCD13182359 UNII:1ULL0QJ8UCUNII-1ULL0QJ8UC
SMILES
CCOc1ccc(cc1)Cc2cc(ccc2Cl)3((((O3)CO)O)O)O
StdInChI
InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
StdInChIKey
JVHXJTBJCFBINQ-ADAARDCZSA-N
Molecular Formula
C21H25ClO6
Molecular Weight
408.873
EINECS
639-683-0
MDL Number
MFCD13182359
Properties
Appearance
white to grayish white powder
Structure
Structure of Dapagliflozin CAS 461432-26-8
Safety Data
Symbol
GHS07, GHS08, GHS09
Signal Word
Warning
Hazard statements
H302 - H319 - H372 - H411
Precautionary Statements
P260 - P264 - P273 - P301 + P312 - P305 + P351 + P338 - P314
WGK Germany
3
MSDS Download
Specifications and Other Information of Our
Identification Methods
Heavy Metals
NMT 10ppm
Water
NMT 2%
Residue on Ignition
NMT 0.5%
Shelf Life
2 years
Storage
Known Application
Dapagliflozin is a sodium-glucose co-transporter 2 inhibitor (SGLT2i) and a new type of oral hypoglycemic drug. It can inhibit SGLT2 activity, inhibit proximal renal tubular sodium-glucose reabsorption, promote urinary glucose excretion, and thereby reduce blood glucose concentration.
General View of Documents
Links
This product is developed by our R&D company Warshel Chemical Ltd (https://www.warshel.com/).
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