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Identification
CAS Number
1441190-66-4
Name
2'3'-cGAMP sodium salt
Synonyms
1441190-66-4
2-Amino-9-octadec-17-yl]-1,9-dihydro-6H-purin- 6-on
2-Amino-9-octadec-17-yl]-1,9-dihydro-6H-purin- 6-one
2-Amino-9-octadéc-17-yl]-1,9-dihydro-6H-purin- 6-one
2′,5′-3′,5′-cGAMP
2′-O,5′-O-((ADENOSINE-3′-O,5′-O-DIYL)BISPHOSPHINICO)GUANOSINE
6H-Purin-6-one, 2-amino-9--1,3,6,9,11,2,10-pentaoxadiphosphacyclot etradecin-7-yl]-1,9-dihydro-
cGAMP(2′-5′)
cyclic
SMILES
Nc1nc2c(ncn22O3COP(=O)(O)O4C@@HC@HO4COP(=O)(O)O23O)c(=O)1
StdInChI
InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(32)12-7(41-18)2-39-45(36,37)43-13-10(31)6(1-38-44(34,35)42-12)40-19(13)30-5-26-9-16(30)27-20(22)28-17(9)33/h3-7,10-13,18-19,31-32H,1-2H2,(H,34,35)(H,36,37)(H2,21,23,24)(H3,22,27,28,33)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1
StdInChIKey
XRILCFTWUCUKJR-INFSMZHSSA-N
Molecular Formula
C20H24N10O13P2
Molecular Weight
674.417
Properties
Appearance
White powder
Safety Data
Symbol
Signal Word
Warning
RIDADR
NONH for all modes of transport
WGK Germany
3
MSDS Download
Specifications and Other Information of Our 2'3'-cGAMP sodium salt CAS 1441190-66-4
Identification Methods
HNMR, HPLC
Purity
95% min
Water
≤3%
Store
Storage at -20 °.
Known Application
1. Innate immunity research: Serves as a potent STING (Stimulat r of Interferon Genes) pathway agonist, widely used to study innate immune responses in humans and animals.
2. Cancer research: Activates the immune system, supporting stuies on tumor immunotherapy.
3. Vaccine adjuvant: Investigated for its potential to enhance vaccine efficacy.
4. Antiviral studies: Used in exploring mechanisms against DNA viruses and some RNA viruses.
5. Drug development: Employed as a candidate molecule or tool compound for developing novel immunomodulatory therapies.
General View of Documents
HNMR of 2'3'-cGAMP sodium salt CAS 1441190-66-4
Links
This product is developed by our R&D company Warshel Chemical Ltd (https://www.warshel.com/).
Quick Inquiry
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