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Exatecan mesilate CAS 16969-90-38
- Identification

- Properties

- Safety Data

- Specifications & Other Information

- Links

- Quick Inquiry

Identification

CAS Number

16969-90-38

Name

Exatecan mesilate

Synonyms

(1S,9S)-1-Amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H,13H-benzopyranoindolizinoquinoline-10,13-dione methanesulfonate (1:1) 10H,13H-Benzopyranoindolizinoquinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S,9S)-, methanesulfonate (1:1) (salt) 169869-90-3 Acide méthanesulfonique - (1S,9S)-1-amino-9-éthyl-5-fluoro-9-hydroxy-4-méthyl-1,2,3,9,12,15-hexahydro-10H,13H-benzopyranoindolizinoquinoléine-10,13-dione (1:1) EXATECAN MESYLATE ANHYDROUSMethansulfonsäure --(1S,9S)-1-amino-9-ethyl-5-fluor-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H,13H-benzopyranoindolizinochinolin-10,13-dion (1:1) (1S,9S)-1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-1,2,3,9,12,15-hexahydro-10H,13H-benzopyranoindolizinoquinoline-10,13-dione,methanesulfonic acid(1S,9S)-1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-2,3,12,15-tetrahydrobenzopyranoindolizinoquinoline-10,13(1H,9H)-dione methanesulfonate169869-90-3 (mesylate)171335-80-1 5-(2,5-Dimethyl-4-(prop-1-en-1-yl)phenoxy)-2,2-dimethylpentanoic acidDX 8951fDX8951fDX-8951fDX8951f;DX 8951f;DX-8951fExatecan (Mesylate)Exatecan mesilateExatecan MeslateExatecan Mesylate MFCD04113012

SMILES

CC1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5cc(c(c6c5c4(CC6)N)C)F)O.CS(=O)(=O)O

StdInChI

InChI=1S/C24H22FN3O4.CH4O3S/c1-3-24(31)14-6-18-21-12(8-28(18)22(29)13(14)9-32-23(24)30)19-16(26)5-4-11-10(2)15(25)7-17(27-21)20(11)19;1-5(2,3)4/h6-7,16,31H,3-5,8-9,26H2,1-2H3;1H3,(H,2,3,4)/t16-,24-;/m0./s1

StdInChIKey

BICYDYDJHSBMFS-GRGFAMGGSA-N

Molecular Formula

C25H26FN3O7S

Molecular Weight

531.553

MDL Number

MFCD04113012

Properties

Appearance

pale yellow solid

Safety Data

Symbol

WGK Germany

3

Specifications and Other Information of Our

Identification Methods

HNMR

Purity

98% min

Shelf Life

2 years

Storage

Store at 2-8℃ for long time, sealed.

Known Application

Exatecan-mesilate is a medication that is primarily used for the treatment of certain cancers. It belongs to a class of drugs called topoisomerase I inhibitors, which work by blocking the replication and repair processes of DNA, inhibiting the growth and spread of cancer cells. Exatecan-mesilate is widely used in the treatment of malignancies such as ovarian cancer and small cell lung cancer. Exatecan-mesilate binds to DNA, inhibiting the activity of topoisomerase I and leading to DNA damage and cell apoptosis in cancer cells.

In addition to being used as a monotherapy, Exatecan-mesilate it can also be used in combination with other anticancer drugs to enhance treatment efficacy. It is employed as a frontline or salvage therapy option, typically determined by healthcare professionals based on the specific circumstances and cancer type of the patient.

General View of Documents

HPLC of exatecan mesilate CAS16969-90-38

NMR of exatecan mesilate CAS16969-90-38

Links

This product is developed by our R&D company Caming Pharmaceutical Limited (https://www.caming.com/).

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Fill out our inquiry form and one of our experts will be in touch with you shortly.
https://www.watson-int.com/exatecan-mesilate-cas-16969-90-38/

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