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5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2
IdentificationPropertiesSafety DataSpecifications & Other InformationLinksQuick Inquiry Identification CAS Number 54857-86-2 Name 5-(Tetradecyloxy)-2-furoic acid (TOFA) Synonyms 2-Furancarboxylic acid, 5-(tetradecyloxy)- 5-(Tetradecyloxy)-2-furoesäure 5-(Tetradecyloxy)-2-furoic acid 5-(tetradecyloxy)furan-2-carboxylic acid54857-86-2 Acide 5-(tétradécyloxy)-2-furoïque MFCD01726059 OLUMACOSTATTOFA5- (tetradecyloxy)-2-furoic acid5-(tetradecyloxy)-2-furancarboxylic acid5396815659-20-1 5-tetradecoxyfuran-2-carboxylic acid5-Tetradecyloxy-2-furonic acid92047-08-0 CARDIODILATINhttps://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:77936RMI-14514SS-4313TOFA - CAS 54857-86-2 - CalbiochemTOFA (5-(Tetradecyloxy)-2-furoic acid)tofa (rmi14514;mdl14514)TOFA, RMI 14514 SMILES CCCCCCCCCCCCCCOc1ccc(o1)C(=O)O StdInChI InChI=1S/C19H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22-18-15-14-17(23-18)19(20)21/h14-15H,2-13,16H2,1H3,(H,20,21) StdInChIKey CZRCFAOMWRAFIC-UHFFFAOYSA-N Molecular Formula C19H32O4 Molecular Weight 324.45 MDL Number MFCD01726059 Properties Appearance White to beige powder Melting Point 112~115°C Safety Data Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves RIDADR  NONH for all modes of transport WGK Germany 2 Specifications and Other Information of Our 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 Identification Methods HNMR, MS, HPLC Purity 97.5%min Solubility(2mg/ml,DMSO) Clear Shelf Life 2 years Storage Store at 2-5℃, keep in dry and aovid direct sun light. Known Application TOFA has been used as a lipid biosynthesis inhibitor in mesenchymal stromal cells (MSCs), human pluripotent stem cells., an acetyl-CoA carboxylase 1 inhibitor in murine adipocyte cell lines., a lipolysis inhibitor in cancer stem cells (CSCs). TOFA has been used as an ACC inhibitor to study its effect on insulin secretion in INS-1E cells TOFA is a cell-permeable, potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC). TOFA is a key enzyme involved in fatty acid biosynthesis. TOFA inhibits cellular fatty acid synthesis in a dose-dependent manner (IC50 = 4 μM in human breast cancer cell line MCF7) General View of Documents HNMR of 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 HPLC of 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 LCMS-1 of 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 LCMS-2 of 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 LCMS-3 of 5-(Tetradecyloxy)-2-furoic acid (TOFA) CAS 54857-86-2 Links This product is developed by our R&D company Watson Bio Ltd (https://www.watson-bio.com/). Quick Inquiry Fill out our inquiry form and one of our experts will be in touch with you shortly.
https://www.watson-int.com/5-tetradecyloxy-2-furoic-acid-tofa-cas-54857-86-2/

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