- Identification

- Properties

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Identification

CAS Number

121660-11-5

Name

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

Synonyms

(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanolméthanol methanol methanolmethanol 121660-11-5 3-Quinolinemethanol, 2-cyclopropyl-4-(4-fluorophenyl)- (2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)met methan-1-ol1346600-49-4 2-cyclopropan-4-(4-fluorophenyl)-3-quinoline methanol2-Cyclopropyl-4-(4-Fluorophenyl) -3-quinolinemethanol2-Cyclopropyl-4-(4-fluorophenyl) -quinolyl-3-methanol2-Cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol-d52-Cyclopropyl-4-(4-Fluorophenyl)quinoline-3-Methanol (en)2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol2-环丙基-4-(4-氟苯基)-3-喹啉甲醇 DS-12057Ethyl 5-amino-1H-pyrrolopyridine-2-carboxylate MFCD09032924 Less…

SMILES

Fc4ccc(c1c3ccccc3nc(c1CO)C2CC2)cc4

StdInChI

InChI=1S/C19H16FNO/c20-14-9-7-12(8-10-14)18-15-3-1-2-4-17(15)21-19(13-5-6-13)16(18)11-22/h1-4,7-10,13,22H,5-6,11H2

StdInChIKey

FIZDBNPUFMDGFZ-UHFFFAOYSA-N

Molecular Formula

C19H16FNO

Molecular Weight

293.335

MDL Number

MFCD09032924

Properties

Appearance

White to light yellow powder or crystal

Safety Data

Symbol

GHS07

Signal Word

Warning

Hazard statements

H302, H315, H319, H335

Precautionary Statements

P261, P305, P338, P351

WGK Germany

3

Specifications and Other Information of Our

Purity

99% min

Melting point

132~137°C

Impurity I(Destluoro)

≤4.1%

Individual impurity

≤0.1%

Total impurities

≤1.0%

Loss on drying

≤0.5%

Shelf Life

2 years

Known Application

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol is an intermediate in the synthesis of Pitavastatin calcium, a statin medication primarily used to lower cholesterol and prevent cardiovascular diseases. As an intermediate, it plays several crucial roles in the drug synthesis process: As an intermediate, 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol helps to enhance the synthesis efficiency of Pitavastatin calcium, making the production process more efficient and controllable.

The quality and purity of the intermediate directly affect the final drug's quality. High-quality intermediates contribute to producing Pitavastatin calcium with higher purity and fewer side effects.

Choosing the appropriate intermediate in the drug synthesis process can minimize unnecessary by-products, thereby reducing the final drug's side effects.

The structure of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol contributes to the pharmacological activity of Pitavastatin calcium, making it more effective in lowering cholesterol and preventing cardiovascular diseases.

General View of Documents

Links

This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).

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