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Identification
CAS Number
591769-05-0
Name
3-CYCLOPENTYLACRYLONITRILE
Synonyms
(2E)-3-Cyclopentyl-2-propenenitrile(2E)-3-Cyclopentylacrylonitril (2E)-3-Cyclopentylacrylonitrile (2E)-3-Cyclopentylacrylonitrile (2E)-3-Cyclopentylprop-2-enenitrile1236033-37-6 2-Propenenitrile, 3-cyclopentyl-, (2E)- 3-cyclopentylprop-2-enenitrile591769-05-0 MFCD11857755 (E)-3-cyclopentylacrylonitrile(E)-3-cyclopentylprop-2-enenitrile 2-Propenenitrile, 3-cyclopentyl- 30459-17-7 3-Cyclopentyl-acrylonitrile95%CA-5126DS-8986
SMILES
C1CCC(C1)/C=C/C#N
StdInChI
InChI=1S/C8H11N/c9-7-3-6-8-4-1-2-5-8/h3,6,8H,1-2,4-5H2/b6-3+
StdInChIKey
VMELXYJYSXXORF-ZZXKWVIFSA-N
Molecular Formula
C8H11N
Molecular Weight
121.180
MDL Number
MFCD11857755
Properties
Appearance
Colorless to pale yellow transparent liquid
Safety Data
Symbol
Signal Word
Warning
WGK Germany
3
MSDS Download
Specifications and Other Information of Our 3-CYCLOPENTYLACRYLONITRILE CAS 591769-05-0
Purity
98% min
Shelf Life
2 years
Storage
Known Application
3-CYCLOPENTYLACRYLONITRILE CAS 591769-05-0, as an intermediate for Ruxolitinib, plays a crucial role in the synthesis of Ruxolitinib. Ruxolitinib is a selective Janus kinase (JAK1 and JAK2) inhibitor, primarily used to treat myelofibrosis and polycythemia vera. Ruxolitinib can inhibit the proliferation and survival of tumor cells, thereby slowing the growth of tumors. Additionally, by inhibiting the JAK-STAT pathway, it can reduce inflammation caused by tumors, alleviating symptoms. The cyclopentyl structure in 3-Cyclopentylacrylonitrile is a crucial part of the Ruxolitinib molecule, essential for the drug's activity and stability. This unique structure helps Ruxolitinib achieve high selectivity and efficacy in targeting JAK1 and JAK2 kinases, enhancing its therapeutic effect.
General View of Documents
Links
This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).
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