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11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE CAS 53067-82-6
- Identification

- Properties

- Safety Data

- Specifications & Other Information

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Identification

CAS Number

53067-82-6

Name

11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE

Synonyms

Validated by Experts, Validated by Users, Non-Validated, Removed by Users(8S,9S,10R,11R,13S,14S)-13-Ethyl-11-hydroxy-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopentaphenanthren-3,17(2H,6H)-dion (8S,9S,10R,11R,13S,14S)-13-Ethyl-11-hydroxy-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopentaphenanthrene-3,17(2H,6H)-dione (8S,9S,10R,11R,13S,14S)-13-Éthyl-11-hydroxy-7,8,9,10,11,12,13,14,15,16-décahydro-1H-cyclopentaphénanthrène-3,17(2H,6H)-dione 53067-82-6 (8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopentaphenanthrene-3,17-dione(8S,9S,10R,11R,13S,14S)-13-ethyl-11-hydroxy-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopentaphenanthrene-3,17(2H)-dione(8S,9S,11R,13S,14S)-13-Ethyl-11-hydroxy-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopentaphenanthrene-3,17(2H,6H)-dione (non-preferred name)11??-hydroxy-13-ethyl-gon-4-ene-3,17-dione11a-Hydroxy-18-methylestr-4-ene-3,17-dione11A-Hydroxy-18-methyl-estr-4-ene-3,17-dioneMFCD22200579

SMILES

CC12C(3(1CCC2=O)CCC4=CC(=O)CC34)O

StdInChI

InChI=1S/C19H26O3/c1-2-19-10-16(21)18-13-6-4-12(20)9-11(13)3-5-14(18)15(19)7-8-17(19)22/h9,13-16,18,21H,2-8,10H2,1H3/t13-,14-,15-,16+,18+,19-/m0/s1

StdInChIKey

JEMKJBGEAVUIOC-ZRTWPRGNSA-N

Molecular Formula

C19H26O3

Molecular Weight

302.408

Properties

Appearance

Off-white crystalline powder

Melting Point

1ss~19s ℃

structure

structure of 11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE CAS 53067-82-6

Safety Data

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Identification Methods

HNMR, HPLC

Assay

90% min

Specific Optical Rotation

-10~-18° (Dioxane)

-3~-13° (Chloroform)

Water

≤0.5%

Loss on Drying

≤0.5%

11 a- Hydroxy -18-methyl-estr-4-ene- 3-one-1713 -ol

≤1.0%

15a-Hydroxy-18-methyl-estra-4-ene-3,17- Dione

≤ 0.5 %

18-methyl-estr-4-ene-3-one-17(3 -ol

≤ 0.5%

18-methyl-estr-4-ene-3,17-dione

≤ 0.5 %

Single Impurity

≤0.5%

Total Impurities

≤ 3.0%

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE possesses antiandrogenic activity. It can bind to androgen receptors, inhibiting the action of androgens. This potential makes Mifepristone useful in the treatment of certain androgen-dependent tumors (such as breast cancer and prostate cancer) and conditions characterized by excessive androgen levels.

And 11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE can bind to glucocorticoid receptors and display some glucocorticoid receptor antagonistic activity. This potential indicates its possible application in the treatment of certain conditions involving glucocorticoid excess and modulation of the biological effects of glucocorticoids.

11A-HYDROXY-18-METHYL-ESTR-4-ENE-3,17-DIONE has also shown other biological activities such as anti-insulin effects, anticoagulant effects, and antitumor effects. These actions are being investigated and explored to further understand the potential clinical applications of Mifepristone.

General View of Documents

Links

This product is developed by our R&D company Warshel Chemical Ltd (https://www.warshel.com/).

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Fill out our inquiry form and one of our experts will be in touch with you shortly.
https://www.watson-int.com/11a-hydroxy-18-methyl-estr-4-ene-317-dione-cas-53067-82-6-2/

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