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Dorzolamide Hydrochloride CAS 130693-82-2
- Identification

- Properties

- Safety Data

- Specifications & Other Information

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Identification

CAS Number

130693-82-2

Name

Dorzolamide Hydrochloride

Synonyms

(4S,6S) 7,7-Dioxyde de 4-(éthylamino)-6-méthyl-5,6-dihydro-4H-thiénothiopyrane-2-sulfonamide, chlorhydrate (1:1) (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide 7,7-dioxide, monohydrochloride(4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thienothiopyran-2-sulfonamid-7,7-dioxidhydrochlorid(4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thienothiopyran-2-sulfonamid-7,7-dioxidhydrochlorid (1:1) (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thienothiopyran-2-sulfonamide 7,7-dioxide hydrochloride(4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thienothiopyran-2-sulfonamide 7,7-dioxide hydrochloride (1:1) (4S,6S)-4-(éthylamino)-6-méthyl-5,6-dihydro-4H-thiénothiopyran-2-sulfonamide-7,7-dioxyde chlorhydrate120279-96-1 130693-82-2 4H-Thienothiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-, hydrochloride (1:1) 4H-thienothiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-, monohydrochlorideDorzolamide (hydrochloride)Dorzolamide HClDorzolamide hydrochlorideMFCD00884659 (2S,4S)-2-Ethylamino-4-methyl-5,5-dioxo-5,7-dithiabicyclonona-8,10-diene-8-sulfonamide hydrochloride(2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-thiophenothiin-6-sulfonamide, chloride(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide 4H-Thienothiopyran-2-sulfonamide hydrochloride(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide 4H-Thienothiopyran-2-sulfonamide, hydrochloride(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-4HH-thieno(2,3-b)thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride(4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thienothiopyran-2-sulfonamide 7,7-dioxide, monohydrochloride(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thienothiopyran-2-sulfonamide(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thienothiopyran-2-sulfonamide hydrochloride(4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thienothiopyran-2-sulfonamide;hydrochloride(4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thienothiopyran-2-sulfonamide 7,7-dioxide hydrochloride(SS,6S)-N-ethyl-6-methyl-2-sulfamoyl-5,6-dihydro-4H-thienothiopyran-4-aminium 7,7-dioxide chloride 120279-36-9 Dorzalamide hydrochlorideDorzolamide Dorzolomide hydrochlorideethyl-thiopyran-4-yl]azanium and chlorideHydrochlorideKS-1348L671152 hydrochlorideL671152 hydrochloride;MK507 hydrochloride;Trusopt hydrochlorideMK507 hydrochlorideTrusopt Trusopt hydrochlorideTrusopt, Cosopt

SMILES

CCN1C(S(=O)(=O)c2c1cc(s2)S(=O)(=O)N)C.Cl

StdInChI

InChI=1S/C10H16N2O4S3.ClH/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16;/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16);1H/t6-,8-;/m0./s1

StdInChIKey

OSRUSFPMRGDLAG-QMGYSKNISA-N

Molecular Formula

C10H17ClN2O4S3

Molecular Weight

360.901

EINECS

620-304-2

Beilstein Registry Number

5896026

MDL Number

MFCD00884659

Properties

Appearance

A white to off white c1ystalline powder.

Safety Data

Symbol

GHS07, GHS08

Signal Word

Warning

Hazard statements

H302 - H373

Precautionary Statements

P260 - P264 - P270 - P301 + P312 - P314 - P501

WGK Germany

3

Specifications and Other Information of Our

Identification Methods

a) I. R: IR Spectrum of sample should concordant with IR Spectrum ofDorzolamide hydrochloride WS.b) HPLC: The retention time of the major peak in the chroma to gr扣n of the assay preparationc) Chloride tes: preparation as obtained in the assay. A white orecioitate should form.

Assay

99% min

Heavy Metals

NMT IO ppm

Water

NMT0.5 %

Limit ofDorzolamide Hydrochloride Related compound A (By HPLC)

NMT0.5%

Residue on Ignition

NMT0.1 %

Residual solvent

Acetone

NMT 5000 ppm

Isopropyl alcohol

NMT 5000 ppm

Ethyl acetate

NMT 5000 ppm

Tetrahydrofuran

NMT720 ppm

Any individual Impurity

NMT 0.1 %

Total Impurities

NMT 0.5%

Shelf Life

2 years

Storage

Under room temperature away from light

Productivity

1MT/month

Known Application

Dorzolamide Hydrochloride is a carbonic anhydrase inhibitor. Dorzolamide hydrochloride is an anti-glaucoma topical eye drops. Dorzolamide hydrochloride is used to reduce the increased intraocular pressure in open angle glaucoma and ocular hypertension

General View of Documents

Links

This product is developed by our R&D company Watsonnoke Scientific Limited (http://www.watsonnoke.com/).

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Fill out our inquiry form and one of our experts will be in touch with you shortly.
https://www.watson-int.com/dorzolamide-hydrochloride-cas-130693-82-2/

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