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IVD (In vitro diagnostic) Material Development

IVD (In vitro diagnostic) Material Development

Jiangsu Watson Bio Ltd was started in early 2021 and acts as a research and development company under FCAD, dedicated to the production and supply of high-quality IVD (In vitro diagnostic) raw materials including enzymes, carbohydrates, antigens, antibodies and custom biochemicals. With a laboratory in Shanghai Jinqiao Development Zone, Jiangsu Watson provides excellent contract outsourcing services (CRO) with after-sale support.Watson has rich experience in enzyme resource exploration, optimization and transformation. It can explore new enzyme sources from huge enzyme resources and optimize and transform the most suitable enzyme molecules. Through the establishment of extensive and in-depth cooperation with the professional enzyme engineering research teams of many famous universities, Watson can grasp the frontier of enzyme engineering in time and quickly transform into the advanced technology of the company.




Watson can perform important enzyme functions such as enzyme activity, stability, substrate specificity, optimum pH, and organic solvent resistance. By rational design, new enzyme resources with greatly improved performance are quickly obtained to meet the application requirements of the target enzyme in different fields such as diagnosis, medicine, energy, washing and papermaking.



TARGET ENZYME


TRANSFORMATION NATURE


RECONSTRUCTION EFFECT

LIPASE


Thermal stability


Increase 230 times

GLYCOSYLTRANSFERASE


Catalytic activity


Increase 380 times

GLUCOSE OXIDASE


Thermal stability


Increase 120 times

CELLULASE


Optimal pH


Reduce 2 pH units

FRUCTOSYLPEPTIDE OXIDASE


Substrate specificity


Selectivity increased 700 times

ESTERASE


Organic solvent resistance


Tolerance of 80% ethanol

Î’-LACTAMASE


Stereoselectivity


Increase 200 times




Proteins usually exist in solution after purification, but the storage time of protein solution is very short. A good freeze-drying process can preserve the activity of most proteins, improve the stability of proteins, prolong the storage time, and reduce the freight.




However, protein freeze-drying may cause loss of protein activity, aggregation and other denaturation problems. Watson has been exploring protein freeze-drying process for many years and has accumulated rich freeze-drying experience. It can customize protein freeze-drying process or optimize its original process for customers.






- Widely recognized brand by our served customers


- Featured products in stock for delivery at any time


- Mature freeze-drying technology to ensure of easy transportation and storage


- Timely after-sales service via email to support the use of our products


- High quality materials with competitive price



- Vitamin: 25-Hydroxyvitamin D, 25-Hydroxyvitamin D3, Vitamin B12 and Folic Acid


- Thyroid Function: Thyroxine t3, Thyroxine t4 and Reverse T3 (rT3)


- Gonad: Estrogen like Estriol / Oestriol / E3, Estradiol / E2 and Estrone / E1; Progesterone like P4 and 17α-OH-Progesterone; Androgen like Testosterone and Androstenedione / A4 / AED / ‘Δ4-dione


- Hypertension: Aldosterone, Cortisol, Angiotensin I, Angiotensin II, Adrenocorticotropic hormone (ACTH / Adrenocorticotropin / Corticotropin), S-Adenosyl-l-homocysteine (SAH), Homocysteine (HCY)


- Therapeutic Drug Monitoring (TDM): Cyclosporine (Cyclosporine A / Ciclosporin), Tacrolimus (FK506), Mycophenolic Acid (Mycophenolate / MPA), Sirolimus (RPM / RAPA / Rapamycin / Rapamune), Carbamazepine (CBZ), Phenytoin (Diphenyl Hydantoin), Valproic Acid (VPA), Phenobarbital (Phenobarbitone / Luminal), Methotrexate (MTX), Vancomycin (INN), Theophylline and Digoxin


- Drug Abuse Test: Oxazepam (Serenid / Serax / Adumbran / Limbial / Vaben), Lorazepam (Ativan / Lorax / Quait / Temesta), Clonazepam (Antelepsin / Darkene / Clonex / Clonopin / Rivotril), Olanzapine (Zyprexa), Paroxetine (Paroxetin / Paroxetinum / Seroxat / Seroxat / Paxil), Methamphetamine, Cocaine (Jam / Erythroxylin / Methylbenzoylecgonine), Amphetamine, Marijuana (Cannabis), Acetaminophen (Paracetamol), Morphine, Oxycodone (Oxycodonum / Thecodine), Benzodiazepine (BZD), Buprenorphine, Phenobarbital (Phenobarbitone / Luminal), Theophylline, Propoxyphene, Opium and Ketamine


https://www.fcad.com/features/ivd-in-vitro-diagnostic-material-development/

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